During the occupation the house was confiscated by the German administration. The Jewish community moved its offices first to today's Kpt. Jaroše, then to an apartment at the then address Koliště 17. Subsequently most Jews of Brno were murdered in Nazi death camps.
After the liberation, the house was reluctantly restituted, but after the communist takeover and in an atmosphere of renewed anti-Jewish persecution as part of the "fight against Zionism", it was taken over by the Czechoslovak state in the 1950s.
The building was used by the Municipal Institute of National Health. The house was declared a cultural monument, but later its monument protection was revoked. After the fall of the communist regime, the Constitutional Court, at the instigation of the Czech Social Security Administration, rejected the complaint of the Jewish Community of Brno, which sought restitution of the house. According to the court, the Jewish community did not use the house before 25 February 1948 and therefore cannot claim restitution.